Glycogen Synthase Kinase 3 beta

A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved in PROTEIN BIOSYNTHESIS and regulates cell growth and proliferation as a component of the WNT SIGNALING PATHWAY and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with PARKINSON DISEASE; ALZHEIMER DISEASE; and BIPOLAR DISORDER.

Also Known As:

GSK-3beta; GSK3B Protein; GSK3beta; GSK 3beta

Macromolecular Substances: 97
- Multiprotein Complexes: 125
  - Axin Signaling Complex: 10
    - Glycogen Synthase Kinase 3: 810
      - Glycogen Synthase Kinase 3 beta: 794
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein Serine-Threonine Kinases: 3588
        Glycogen Synthase Kinases: 841
        Glycogen Synthase Kinase 3: 810
        Glycogen Synthase Kinase 3 beta: 794
        Proline-Directed Protein Kinases: 28
        Glycogen Synthase Kinase 3: 810
        Glycogen Synthase Kinase 3 beta: 794
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3588
      - Glycogen Synthase Kinases: 841
        Glycogen Synthase Kinase 3: 810
        Glycogen Synthase Kinase 3 beta: 794
      - Proline-Directed Protein Kinases: 28
        Glycogen Synthase Kinase 3: 810
        Glycogen Synthase Kinase 3 beta: 794
    - Axin Signaling Complex: 10
      - Glycogen Synthase Kinase 3: 810
        Glycogen Synthase Kinase 3 beta: 794

M Hagve Selected Research

M Hagve Research Topics

Disease

Drug/Important Bio-Agent (IBA)